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Anti-KLHL3 Polyclonal Antibody

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货号 TMAB-08110

Anti-KLHL3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KLHL3。Anti-KLHL3 Polyclonal Antibody 可用于 WB。

Anti-KLHL3 Polyclonal Antibody

Anti-KLHL3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08110

Anti-KLHL3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KLHL3。Anti-KLHL3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-KLHL3 Polyclonal Antibody is a Rabbit antibody targeting KLHL3. Anti-KLHL3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton. Cytoplasm, cytosol.
组织特异性Widely expressed.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景KLHL3 protein contains a poxvirus and zinc finger domain at the N-terminus and six tandem repeats (kelch repeats) at the C-terminus. At the amino acid level, KLHL3 shares 77% similarity with Drosophila kelch and 89% similarity with Mayven (KLHL2), another human kelch homolog. At least three isoforms are produced and may be the result of alternative promoter usage. The KLHL3 maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, no inactivating mutations of KLHL3 could be detected in malignant myeloid disorders with loss of 5q.
抗原信息
免疫原
KLH conjugated synthetic peptide: human KLHL3
抗原种属
Human
基因名称
KLHL3
基因ID
蛋白名称
Kelch-like protein 3
功能
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex may act by mediating ubiquitination of SLC12A3/NCC, thereby regulating SLC12A3/NCC subcellular location at the cell membrane.
化学信息
分子量Theoretical: 65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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