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S100A6 Protein, Human, Recombinant (His)

产品编号 TMPY-01339

别名: 2A9, PRA, CABP, CACY, S100 calcium binding protein A6, 5B10

S100A6 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12 kDa and the accession number is P06703.

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S100A6 Protein, Human, Recombinant (His)

规格	价格/CNY		货期	数量
50 μg	￥ 3,820		5日内发货

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生物活性	Testing in progress
产品描述	S100A6 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12 kDa and the accession number is P06703.

种属	Human
表达系统	Baculovirus Insect Cells
标签	C-His
蛋白编号	P06703
别名	2A9, PRA, CABP, CACY, S100 calcium binding protein A6, 5B10
蛋白构建	The Human S100A6 (NP_055439.1) (Met 1-Gly 90) was expressed, with a C-terminal polyhistidine tag.
蛋白纯度	> 96 % as determined by SDS-PAGE
分子量	12 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 100 mM NaCl, 0.5 mM PMSF, 1 mM TCEP, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. S100A6 (S100 calcium-binding protein A6) is a member of the S100 family of proteins, and functions in prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma.

参考文献

1. Schäfer, B.W. et al., 1996, Trends Biochem. Sci. 21 (4): 134-140. 2. Donato,R. et al., 2003, Microsc. Res. Tech. 60 (6): 540-551. 3. Nowotny, M. et al., 2003, J. Biol. Chem. 278 (29): 26923-26928. 4. Nonaka D, et al., 2008, J. Cutan. Pathol. 35 (11): 1014-1019. 5. Marenholz, I. et al., 2004, Biochem. Biophys. Res. Commun. 322 (4): 1111-22.

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Keywords

S100A6 Protein, Human, Recombinant (His) 2A9 PRA CABP CACY S100 calcium binding protein A6 5B10 recombinant recombinant-proteins proteins protein

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