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Anti-CD16/FCGR3 Antibody-APC (1A938) 是一种 APC-conjugated Mouse 抗体,靶向 CD16/FCGR3。Anti-CD16/FCGR3 Antibody-APC (1A938) 可用于 FCM。
Anti-CD16/FCGR3 Antibody-APC (1A938) 是一种 APC-conjugated Mouse 抗体,靶向 CD16/FCGR3。Anti-CD16/FCGR3 Antibody-APC (1A938) 可用于 FCM。
产品描述 | Anti-CD16/FCGR3 Antibody-APC (1A938) is a APC-conjugated Mouse antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody-APC (1A938) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 1A938 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human CD16 expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human CD16. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
应用 | FCM |
推荐剂量 | 5 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD16a/Fc gamma RIIIa (rh CD16a/Fc gamma RIIIa; TMPY-00763; P08637-1; Met1-Gln208,176F) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
研究背景 | Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes. |
偶联 | APC |
其他可选修饰符 | Unconjugated/PerCP/FITC/PE |
可提供抗体种类 | 5 |
免疫原 | Recombinant Human CD16a/Fc gamma RIIIa Protein (TMPY-00763) |
抗原种属 | Human |
研究领域 | Fc Receptors |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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