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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Alas1 Antibody (2R254)

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货号 TMAB-02425

Anti-Alas1 Antibody (2R254) 是一种 Rabbit 抗体，靶向 Alas1。Anti-Alas1 Antibody (2R254) 可用于 WB。

Anti-Alas1 Antibody (2R254)

Anti-Alas1 Antibody (2R254)

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Rating icon 还可以
货号 TMAB-02425

Anti-Alas1 Antibody (2R254) 是一种 Rabbit 抗体，靶向 Alas1。Anti-Alas1 Antibody (2R254) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,485
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-Alas1 Antibody (2R254) is a Rabbit antibody targeting Alas1. Anti-Alas1 Antibody (2R254) can be used in WB.
Ig Type
IgG
克隆号
2R254
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Mitochondrion matrix
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, NF-E2 and EKLF. Since the ALAS gene maps to the X chromosome, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia.
抗原信息
免疫原
Recombinant Protein: human Alas1 C-terminal 200aa
抗原种属
Human
基因名称
ALAS1
基因ID
211
蛋白名称
5-aminolevulinate synthase, nonspecific, mitochondrial
Uniprot ID
P13196
化学信息
分子量Theoretical: 65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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