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Anti-CCR5 Polyclonal Antibody
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产品编号 TMAB-00325
Anti-CCR5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CCR5。Anti-CCR5 Polyclonal Antibody 可用于 WB。
Anti-CCR5 Polyclonal Antibody
Anti-CCR5 Polyclonal Antibody
还可以产品编号 TMAB-00325
Anti-CCR5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CCR5。Anti-CCR5 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-CCR5 Polyclonal Antibody is a Rabbit antibody targeting CCR5. Anti-CCR5 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | Sample: Lane 1: Human THP-1 cell lysates Lane 2: Human U937 cell lysates Primary: Anti-CCR-5 (TMAB-00325) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 43 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]. |
| 免疫原 | KLH conjugated synthetic peptide: human CCR-5 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | GPCR,Chemokines,HIV-related,Beta Chemokine Rec. (CCR),Macrophage / Inflamm.,Host Virus Interaction,Alzheimer's disease,GPCR |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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