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Anti-YAP1 Antibody (3O376)
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产品编号 TMAC-04307
Anti-YAP1 Antibody (3O376) 是一种 Mouse 抗体，靶向 YAP1。Anti-YAP1 Antibody (3O376) 可用于 WB,IP,IF。
Anti-YAP1 Antibody (3O376)
Anti-YAP1 Antibody (3O376)
还可以产品编号 TMAC-04307
Anti-YAP1 Antibody (3O376) 是一种 Mouse 抗体，靶向 YAP1。Anti-YAP1 Antibody (3O376) 可用于 WB,IP,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,980 | 5日内发货 | |
| 100 μL | ¥ 2,980 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-YAP1 Antibody (3O376) is a Mouse antibody targeting YAP1. Anti-YAP1 Antibody (3O376) can be used in WB,IP,IF. |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of YAP expression in non-transfected 293T (A), human YAP transfected 293T (B) and Caco-2 (C) whole cell lysates. |
| 应用 | |
| 推荐剂量 | WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The Yes-associated protein, otherwise known as YAP, is a 14-3-3-bindingmolecule that was originally recognized by virtue of its ability to bind to theSH3 domain of Yes. The binding of YAP to 14-3-3 requires the phosphorylationof a homologous serine residue (Ser 112) in the YAP 14-3-3-binding motif. Thehighly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation,cell cycle progression and apoptosis by binding intracellular phosphoproteinsinvolved in signal transduction. YAP may link events at the plasmamembrane and cytoskeleton to inhibition of transcription in the nucleus in amanner regulated by 14-3-3 proteins. YAP shares homology with the WWdomain of TAZ, transcriptional co-activator with PDZ-binding motif, whichfunctions as a transcriptional co-activator by binding to the PPXY motif presentin transcription factors. YAP is expressed at high levels in the lung, placenta,prostate, ovary and testis. |
| 偶联 | Unconjugated |
| 免疫原 | Amino acids 294-323 within an internal region of YAP of human origin |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 65 kDa. |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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