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别名 KRM2, Kremen-2, KREMEN2, Dickkopf receptor 2
Anti-Kremen-2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Kremen-2。Anti-Kremen-2 Polyclonal Antibody 可用于 WB。
Anti-Kremen-2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Kremen-2。Anti-Kremen-2 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-Kremen-2 Polyclonal Antibody is a Rabbit antibody targeting Kremen-2. Anti-Kremen-2 Polyclonal Antibody can be used in WB. |
| 别名 | KRM2, Kremen-2, KREMEN2, Dickkopf receptor 2 |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human,Dog,Sheep) |
| 验证活性 | 1. Sample: Cerebellum (Mouse) Lysate at 40 μg Cerebellum (Rat) Lysate at 40 μg Primary: Anti-KREMEN2 (TMAB-01035) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kDa Observed band size: 48 kDa 2. Sample: Cerebrum (Mouse) Lysate at 40 μg Primary: Anti-KREMEN2 (TMAB-01035) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 46 kDa Observed band size: 46 kDa ![]() ![]() |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
| 免疫原 | KLH conjugated synthetic peptide: human KREMEN2 |
| 抗原种属 | Human |
| 基因名称 | KREMEN2 |
| 基因ID | |
| 蛋白名称 | Kremen protein 2 |
| Uniprot ID | |
| 功能 | Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. Forms a ternary complex with Dkk1 and LRP6 and induces rapid endocytosis and removal of the Wnt receptor LRP6 from the plasma membrane. |
| 分子量 | Theoretical: 46 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |