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Anti-Kremen-2 Polyclonal Antibody

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货号 TMAB-01035

别名 KRM2, Kremen-2, KREMEN2, Dickkopf receptor 2

Anti-Kremen-2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Kremen-2。Anti-Kremen-2 Polyclonal Antibody 可用于 WB。

Anti-Kremen-2 Polyclonal Antibody

Anti-Kremen-2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-01035 别名 KRM2, Kremen-2, KREMEN2, Dickkopf receptor 2

Anti-Kremen-2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Kremen-2。Anti-Kremen-2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-Kremen-2 Polyclonal Antibody is a Rabbit antibody targeting Kremen-2. Anti-Kremen-2 Polyclonal Antibody can be used in WB.
别名KRM2, Kremen-2, KREMEN2, Dickkopf receptor 2
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Sheep)
验证活性
1. Sample:
Cerebellum (Mouse) Lysate at 40 μg
Cerebellum (Rat) Lysate at 40 μg
Primary: Anti-KREMEN2 (TMAB-01035) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kDa
Observed band size: 48 kDa
2. Sample:
Cerebrum (Mouse) Lysate at 40 μg
Primary: Anti-KREMEN2 (TMAB-01035) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 46 kDa
Observed band size: 46 kDa
verifiedActivityverifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human KREMEN2
抗原种属
Human
基因名称
KREMEN2
基因ID
蛋白名称
Kremen protein 2
Uniprot ID
功能
Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. Forms a ternary complex with Dkk1 and LRP6 and induces rapid endocytosis and removal of the Wnt receptor LRP6 from the plasma membrane.
化学信息
分子量Theoretical: 46 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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