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顶部生物活性储存和溶解信息计算器

Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 2

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Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 2
产品编号 TMAC-03813
别名 SNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246), p-SNAI1 (S246)

Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-SNAI1 (Ser246)。Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 可用于 WB,IF。

Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 2

Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 2

Rating icon 还可以
Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 2
产品编号 TMAC-03813 别名 SNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246), p-SNAI1 (S246)

Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-SNAI1 (Ser246)。Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody 可用于 WB,IF。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,235
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SNAI1 (Ser246). Anti-Phospho-SNAI1 (Ser246) Polyclonal Antibody can be used in WB,IF.
别名SNAI1 (p-Ser246), SNAI1 (p-S246), p-SNAI1 (Ser246), p-SNAI1 (S246)
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Western blot analysis of extracts from HT29 cells using SNAI1 (Phospho-Ser246) Antibody TMAC-03813. The lane on the right is treated with the antigen-specific peptide.
2. Immunofluorescence staining of methanol-fixed HuvEc cells using SNAI1 (Phospho-Ser246) Antibody TMAC-03813.
应用
WB
IF
推荐剂量
WB: 1:500-1000; IF: 1:100-200
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up-regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of Serine 246(T-F-S(p)-R-M) derived from Human SNAI1
抗原种属
human
Uniprot ID
O95863
化学信息
分子量Actual: 29 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

SNAI1 (pSer246)SNAI1 (pS246)SNAI1 (phospho-Ser246)SNAI1 (phospho-S246)pSNAI1 (Ser246)pSNAI1 (S246)

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4个月前
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