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Anti-LRP/MVP Polyclonal Antibody

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货号 TMAB-08393

Anti-LRP/MVP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LRP/MVP。Anti-LRP/MVP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-LRP/MVP Polyclonal Antibody

Anti-LRP/MVP Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08393

Anti-LRP/MVP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LRP/MVP。Anti-LRP/MVP Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-LRP/MVP Polyclonal Antibody is a Rabbit antibody targeting LRP/MVP. Anti-LRP/MVP Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,GuineaPig)
应用IHC-PIHC-FrICC/IFIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus, nuclear pore complex.
组织特异性Present in most normal tissues. Higher expression observed in epithelial cells with secretory and excretory functions, as well as in cells chronically exposed to xenobiotics, such as bronchial cells and cells lining the intestine. Overexpressed in many multidrug-resistant cancer cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
抗原信息
免疫原
KLH conjugated synthetic peptide: human LRP
抗原种属
Human
基因名称
MVP
基因ID
9961
蛋白名称
Major vault protein
Uniprot ID
Q14764
功能
Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
化学信息
分子量Theoretical: 99 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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