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Anti-Clusterin Antibody-FITC (8L482)
还可以产品编号 TMAY-01836F
Anti-Clusterin Antibody-FITC (8L482) 是一种 FITC-conjugated Rabbit 抗体，靶向 Clusterin。Anti-Clusterin Antibody-FITC (8L482) 可用于 FCM。
Anti-Clusterin Antibody-FITC (8L482)
Anti-Clusterin Antibody-FITC (8L482)
还可以产品编号 TMAY-01836F
Anti-Clusterin Antibody-FITC (8L482) 是一种 FITC-conjugated Rabbit 抗体，靶向 Clusterin。Anti-Clusterin Antibody-FITC (8L482) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-Clusterin Antibody-FITC (8L482) is a FITC-conjugated Rabbit antibody targeting Clusterin. Anti-Clusterin Antibody-FITC (8L482) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8L482 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CLU expression in A549 cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with FITC Rabbit anti-Human CLU. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Clusterin / Apolipoprotein J / Apo-J (rh Clusterin / Apolipoprotein J / Apo-J; TMPY-01691; NP_001822.2; Met1-Glu501) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's disease. Its major form, a heterodimer, is secreted and present in physiological fluids, but truncated forms targeted to the nucleus have also been identified. Clusterin/Apolipoprotein J/Apo-J is a widely distributed glycoprotein with a wide range of biologic properties. A prominent and defining feature of clusterin is its marked induction in such disease states as glomerulonephritis, cystic renal disease, renal tubular injury, neurodegenerative conditions, atherosclerosis, and myocardial infarction. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others. |
| 偶联 | FITC |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human Clusterin / Apolipoprotein J / Apo-J protein (TMPY-01691) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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