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Anti-Phospho-ALOX5 (Ser524) Polyclonal Antibody

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货号 TMAB-10306

Anti-Phospho-ALOX5 (Ser524) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-ALOX5 (Ser524)。Anti-Phospho-ALOX5 (Ser524) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-ALOX5 (Ser524) Polyclonal Antibody

Anti-Phospho-ALOX5 (Ser524) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-10306

Anti-Phospho-ALOX5 (Ser524) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-ALOX5 (Ser524)。Anti-Phospho-ALOX5 (Ser524) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-ALOX5 (Ser524) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ALOX5 (Ser524). Anti-Phospho-ALOX5 (Ser524) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus matrix. Nucleus membrane; Peripheral membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human 5-Lipoxygenase around the phosphorylation site of Ser524
抗原种属
Human
基因名称
ALOX5
基因ID
240
蛋白名称
Polyunsaturated fatty acid 5-lipoxygenase
Uniprot ID
P09917
功能
Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.
化学信息
分子量Theoretical: 78 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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