SjDX5-53 control peptide serves as a control for the TLR2 activator SjDX5-53, without targeting specific receptors or influencing regulatory T cells (Tregs) or dendritic cells. It is useful for excluding nonspecific effects and confirming SjDX5-53’s specific role in Tregs induction and autoimmune disease mitigation. This peptide is applied in research on autoimmune diseases like colitis and psoriasis.