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Anti-Transferrin Antibody (3L945)
还可以产品编号 TMAY-01470
Anti-Transferrin Antibody (3L945) 是一种 Mouse 抗体，靶向 Transferrin。Anti-Transferrin Antibody (3L945) 可用于 ELISA(Cap)。
Anti-Transferrin Antibody (3L945)
Anti-Transferrin Antibody (3L945)
还可以产品编号 TMAY-01470
Anti-Transferrin Antibody (3L945) 是一种 Mouse 抗体，靶向 Transferrin。Anti-Transferrin Antibody (3L945) 可用于 ELISA(Cap)。
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偶联与修饰
抗原信息
| 产品描述 | Anti-Transferrin Antibody (3L945) is a Mouse antibody targeting Transferrin. Anti-Transferrin Antibody (3L945) can be used in ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3L945 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Transferrin / TF (rh Transferrin / TF; TMPY-01279; NP_001054.1; Met1-Pro698). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Transferrin is a glycoprotein with an approximate molecular weight of 76.5 kDa. This glycoprotein is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of Transferrin is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte / pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. Transferrins are iron binding transport proteins that bind Fe3+ion in association with the binding of an anion, usually bicarbonate. This transferrin binds only one Fe3+ion per protein molecule. Transports iron ions from the hemolymph into the eggs during the vitellogenic stage. Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. When a transferrin loaded with iron encounters with a transferring receptor on cell surface, transferring binds to it and, as a consequence, is transported into the cell in a visicle by receptor-mediated endocytosis. The PH is reduced by hydrogen iron pumps. The lower pH causes transferrin to release its iron ions. The receptor is then transported through the endocytic cycle back to the cell surface, ready for another round of iron uptake. Each transferrin molecule has the ability to carry two iron ions in the ferric form. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Transferrin / TF Protein (TMPY-01279) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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