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CD48 Protein, Human, Recombinant (hFc & Avi), Biotinylated

产品编号 TMPY-06299

别名: CD48 molecule, Blast-1, hCD48, BCM1, MEM-102, mCD48, SLAMF2, BLAST1, BLAST

CD48 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 50.88 kDa and the accession number is P09326-1.

TargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

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CD48 Protein, Human, Recombinant (hFc & Avi), Biotinylated

规格	价格/CNY		货期	数量
20 μg	￥ 2,940		5日内发货
100 μg	￥ 6,800		5日内发货

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参考文献

生物活性	Immobilized Human 2B4/CD244 (His Tag) at 2 μg/mL (100 μL/well) can bind Human CD48 (hFc & AVI Tag), Biotinylated, the EC50 of Human CD48 (hFc & AVI Tag), Biotinylated is 15-120 ng/mL.
产品描述	CD48 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 50.88 kDa and the accession number is P09326-1.

种属	Human
表达系统	HEK293 Cells
标签	C-hFc-Avi
蛋白编号	P09326-1
别名	CD48 molecule, Blast-1, hCD48, BCM1, MEM-102, mCD48, SLAMF2, BLAST1, BLAST
蛋白构建	The Human CD48 (NP_001769.2)(Met1-Ser220) was expressed with a c-terminal AVI tagged Fc region of Human IgG1 at the C-terminus (Fc-AVI). The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
蛋白纯度	> 95 % as determined by SDS-PAGE.
分子量	50.88 kDa (predicted)

内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IHC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy

参考文献

1. Messmer B,et al.(2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50. 2. Milstein O,et al.(2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.

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Keywords

CD48 Protein, Human, Recombinant (hFc & Avi), Biotinylated MEM102 CD48 molecule BLAST 1 SLAMF-2 Blast-1 BCM 1 hCD48 BCM1 MEM-102 mCD48 SLAMF2 BLAST1 BCM-1 MEM 102 BLAST SLAMF 2 recombinant recombinant-proteins proteins protein

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