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Anti-CLPS Antibody (5Z220)
还可以产品编号 TMAY-02611
别名 colipase, pancreatic
Anti-CLPS Antibody (5Z220) 是一种 Mouse 抗体，靶向 CLPS。Anti-CLPS Antibody (5Z220) 可用于 IHC-P。
Anti-CLPS Antibody (5Z220)
Anti-CLPS Antibody (5Z220)
还可以产品编号 TMAY-02611 别名 colipase, pancreatic
Anti-CLPS Antibody (5Z220) 是一种 Mouse 抗体，靶向 CLPS。Anti-CLPS Antibody (5Z220) 可用于 IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,694 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CLPS Antibody (5Z220) is a Mouse antibody targeting CLPS. Anti-CLPS Antibody (5Z220) can be used in IHC-P. |
| 别名 | colipase, pancreatic |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5Z220 |
| 交叉反应 | Human |
| 验证活性 | Immunochemical staining of human CLPS in human pancreas with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:100-1:500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Colipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five conserved disulphide bonds. Structural analogies have been recognised between a developmental protein, the pancreatic lipase C-terminal domain, the N-terminal domains of lipoxygenases and the C-terminal domain of alpha-toxin. Colipase can only be detected in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Colipase allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. Colipase is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilising as active conformation and considerably increasing the overall hydrophobic binding site. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CLPS Protein (TMPY-02846) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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