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OMGP Protein, Human, Recombinant (aa 1-420, His)

OMGP Protein, Human, Recombinant (aa 1-420, His)

产品编号 TMPY-02086
别名: OMGP, oligodendrocyte myelin glycoprotein

OMGP Protein, Human, Recombinant (aa 1-420, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P23515-1.

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OMGP Protein, Human, Recombinant (aa 1-420, His)
规格 价格/CNY 货期 数量
50 μg ¥ 3,820 5日内发货
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产品目录号及名称: OMGP Protein, Human, Recombinant (aa 1-420, His) (TMPY-02086)
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生物活性 Testing in progress
产品描述 OMGP Protein, Human, Recombinant (aa 1-420, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P23515-1.
种属 Human
表达系统 HEK293 Cells
标签 C-His
蛋白编号 P23515-1
别名 OMGP, oligodendrocyte myelin glycoprotein
蛋白构建 The mature form of Human OMGP (P23515-1) (Met 1-Asn 420) without the pro peptide was expressed, fused with a polyhistidine tag at the C-terminus.
蛋白纯度 > 97 % as determined by SDS-PAGE
分子量 46 kDa (predicted)
内毒素 < 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice.

研究背景 Oligodendrocyte-myelin glycoprotein, also known as OMG and OMGP, is a cell membrane protein that contains eight LRR (leucine-rich) repeats. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG / OMGP play roles in both the developing and adult central nervous system. OMG / OMGP participates in growth cone collapse and inhibition of neurite outgrowth through its interaction with NgR, the receptor for Nogo. This function requires its leucine-rich repeat domain, a highly conserved region in OMgp during mammal evolution. OMG / OMGP leucine-rich repeat domain is also implicated in the inhibition of cell proliferation. OMG / OMGP may also be involved in the formation and maintenance of myelin sheaths. Cell proliferation, neuronal sprouting, and myelination are crucial processes involved in brain development and regeneration after injury.

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Keywords

OMGP Protein, Human, Recombinant (aa 1-420, His) OMGP oligodendrocyte myelin glycoprotein recombinant recombinant-proteins proteins protein

 

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