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Anti-PD-L2 Antibody (6M31)

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产品编号 TMAY-00568

Anti-PD-L2 Antibody (6M31) 是一种 Mouse 抗体,靶向 PD-L2。Anti-PD-L2 Antibody (6M31) 可用于 ELISA(Cap)。

Anti-PD-L2 Antibody (6M31)

Anti-PD-L2 Antibody (6M31)

Rating icon 还可以
产品编号 TMAY-00568

Anti-PD-L2 Antibody (6M31) 是一种 Mouse 抗体,靶向 PD-L2。Anti-PD-L2 Antibody (6M31) 可用于 ELISA(Cap)。

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产品介绍

生物活性
产品描述
Anti-PD-L2 Antibody (6M31) is a Mouse antibody targeting PD-L2. Anti-PD-L2 Antibody (6M31) can be used in ELISA(Cap).
Ig Type
Monoclonal Mouse IgG1
克隆号
6M31
交叉反应
Human
应用
ELISA(Cap)
抗体种类
Monoclonal
宿主来源Mouse
构建方式This product is a recombinant monoclonal antibody expressed from HEK293 cells.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Programmed death ligand 2 (PD-L2), also referred to as B7-DC and CD273, is a member of the B7 family of proteins including B7-1, B7-2, B7-H2, B7-H1 (PD-L1), and B7-H3. PD-L2 is a type I membrane protein and structurally consists of an extracellular region containing one V-like and one C-like Ig domain, a transmembrane region, and a short cytoplasmic domain. PD-L2 is expressed on antigen presenting cells, placental endothelium and medullary thymic epithelial cells, and can be induced by LPS in B cells, INF-γ in monocytes, or LPS plus IFN-γ in dendritic cells. The CD28 and B7 protein families are critical regulators of immune responses. PD-L2 and PD-L1 are two ligands for PD-1, member of the CD28/CTLA4 family expressed on activated lymphoid cells, and thus provide signals for regulating T cell activation and immune tolerance. The interaction of B7-DC/PD-1 exhibited a 2-6-fold higher affinity compared with the interaction of B7-H1/PD-1.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human PD-L2/B7-DC/CD273 Protein (TMPY-04346)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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4个月前
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