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Anti-Proteasome 26S S2 Polyclonal Antibody

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货号 TMAB-11804

Anti-Proteasome 26S S2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Proteasome 26S S2。Anti-Proteasome 26S S2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Proteasome 26S S2 Polyclonal Antibody

Anti-Proteasome 26S S2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11804

Anti-Proteasome 26S S2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Proteasome 26S S2。Anti-Proteasome 26S S2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-Proteasome 26S S2 Polyclonal Antibody is a Rabbit antibody targeting Proteasome 26S S2. Anti-Proteasome 26S S2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Proteasome 26S S2/TRAP2
抗原种属
Human
基因名称
PSMD2
基因ID
5708
蛋白名称
26S proteasome non-ATPase regulatory subunit 2
Uniprot ID
Q13200
功能
Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
化学信息
分子量Theoretical: 100 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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