购物车
- 全部删除
您的购物车当前为空
Anti-TRPM8 Antibody (1W708)
还可以产品编号 TMAH-01215
别名 Trp-p8, TRPP8, TRPM 8, Transient receptor potential p8, Transient receptor potential cation channel subfamily M member 8, LTrpC-6, LTRPC6, LTrpC6, Long transient receptor potential channel 6
Anti-TRPM8 Antibody (1W708) 是一种抗体，靶向 TRPM8。Anti-TRPM8 Antibody (1W708) 可用于 ELISA, IHC。
Anti-TRPM8 Antibody (1W708)
Anti-TRPM8 Antibody (1W708)
还可以产品编号 TMAH-01215 别名 Trp-p8, TRPP8, TRPM 8, Transient receptor potential p8, Transient receptor potential cation channel subfamily M member 8, LTrpC-6, LTRPC6, LTrpC6, Long transient receptor potential channel 6
Anti-TRPM8 Antibody (1W708) 是一种抗体，靶向 TRPM8。Anti-TRPM8 Antibody (1W708) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-TRPM8 Antibody (1W708) is an antibody targeting TRPM8. Anti-TRPM8 Antibody (1W708) can be used in ELISA, IHC. |
| 别名 | Trp-p8, TRPP8, TRPM 8, Transient receptor potential p8, Transient receptor potential cation channel subfamily M member 8, LTrpC-6, LTRPC6, LTrpC6, Long transient receptor potential channel 6 |
| Ig Type | Rabbit IgG |
| 克隆号 | 1W708 |
| 交叉反应 | Human |
| 验证活性 | IHC image of TMAH-01215 diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| 应用 | ELISA, IHC |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Membrane raft. Endoplasmic reticulum membrane. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonist menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing. In prostate cancer cells, shows strong inward rectification and high calcium selectivity in contrast to its behavior in normal cells which is characterized by outward rectification and poor cationic selectivity. Plays a role in prostate cancer cell migration. Isoform 2 and isoform 3 negatively regulate menthol- and cold-induced channel activity by stabilizing the closed state of the channel. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human TRPM8 |
| 抗原种属 | Human |
| 基因ID | 79054 |
| Uniprot ID | |
| 研究领域 | Neuroscience, Cancer, Metabolism, Signal transduction |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-TRPM8 Antibody (1W708) | purchase Anti-TRPM8 Antibody (1W708) | Anti-TRPM8 Antibody (1W708) cost | order Anti-TRPM8 Antibody (1W708)
嗨！有任何问题？点我咨询
评论内容