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Anti-PRAME Polyclonal Antibody

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货号 TMAB-11709

Anti-PRAME Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PRAME。Anti-PRAME Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-PRAME Polyclonal Antibody

Anti-PRAME Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11709

Anti-PRAME Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PRAME。Anti-PRAME Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-PRAME Polyclonal Antibody is a Rabbit antibody targeting PRAME. Anti-PRAME Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 0.2μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus (Probable). Cell membrane.
组织特异性Expressed in testis. Detected in samples of kidney, brain and skin.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human PRAME
抗原种属
Human
基因名称
PRAME
基因ID
蛋白名称
Melanoma antigen preferentially expressed in tumors
Uniprot ID
功能
Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis.
化学信息
分子量Theoretical: 56 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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