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Anti-PRAME Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PRAME。Anti-PRAME Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。
Anti-PRAME Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PRAME。Anti-PRAME Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-PRAME Polyclonal Antibody is a Rabbit antibody targeting PRAME. Anti-PRAME Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse |
| 应用 | IHC-PIHC-FrIFFCM |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 0.2μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus (Probable). Cell membrane. |
| 组织特异性 | Expressed in testis. Detected in samples of kidney, brain and skin. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed in acute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human PRAME |
| 抗原种属 | Human |
| 基因名称 | PRAME |
| 基因ID | |
| 蛋白名称 | Melanoma antigen preferentially expressed in tumors |
| Uniprot ID | |
| 功能 | Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. |
| 分子量 | Theoretical: 56 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |