Asfotase alfa (ENB-0040), a bone-targeted genetically engineered glycoprotein, enhances survival, bone mineralization, and growth while preventing mineralization defects in the feet, rib cage, lower limbs, and jaws of Akp2 −/− knockout mice. It has applications in researching perinatal, infantile, and juvenile-onset hypophosphatasia (HPP) [1].

Human

Monoclonal

Unconjugated