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Anti-CD204 Monoclonal Antibody (4M704)

Synonyms: SR-AIII, SR-AII, SR-AI, SR-A, SRA, SCARA1, phSR2, phSR1, MSR1
货号 TMAT-0319 一键复制产品信息
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Anti-CD204 Monoclonal Antibody (4M704) 是一种 Mouse 抗体,靶向 CD204。Anti-CD204 Monoclonal Antibody (4M704) 可用于 WB,FCM。

Anti-CD204 Monoclonal Antibody (4M704)

一键复制产品信息
Rating icon 还可以
货号 TMAT-0319

别名 SR-AIII, SR-AII, SR-AI, SR-A, SRA, SCARA1, phSR2, phSR1, MSR1

Anti-CD204 Monoclonal Antibody (4M704) 是一种 Mouse 抗体,靶向 CD204。Anti-CD204 Monoclonal Antibody (4M704) 可用于 WB,FCM。

Anti-CD204 Monoclonal Antibody (4M704)
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产品介绍


生物活性
产品描述
Anti-CD204 Monoclonal Antibody (4M704) is a Mouse antibody targeting CD204. Anti-CD204 Monoclonal Antibody (4M704) can be used in WB,FCM.
别名
SR-AIII, SR-AII, SR-AI, SR-A, SRA, SCARA1, phSR2, phSR1, MSR1
Ig Type
IgG1
克隆号
4M704
反应种属
Human
应用WBFCM
推荐剂量
WB: 1/500-1/2000; FCM: 1/200-1/400
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液PBS with 0.05% sodium azide
浓度1 mg/ml
研究背景This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of human CD204 (AA: extra 275-451) expressed in E. Coli.
抗原种属
Human
基因名称
MSR1
基因ID
蛋白名称
Macrophage scavenger receptor types I and II
Uniprot ID
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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