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Anti-CD204 Monoclonal Antibody (4M704) 是一种 Mouse 抗体,靶向 CD204。Anti-CD204 Monoclonal Antibody (4M704) 可用于 WB,FCM。
别名 SR-AIII, SR-AII, SR-AI, SR-A, SRA, SCARA1, phSR2, phSR1, MSR1
Anti-CD204 Monoclonal Antibody (4M704) 是一种 Mouse 抗体,靶向 CD204。Anti-CD204 Monoclonal Antibody (4M704) 可用于 WB,FCM。

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| 产品描述 | Anti-CD204 Monoclonal Antibody (4M704) is a Mouse antibody targeting CD204. Anti-CD204 Monoclonal Antibody (4M704) can be used in WB,FCM. |
| 别名 | SR-AIII, SR-AII, SR-AI, SR-A, SRA, SCARA1, phSR2, phSR1, MSR1 |
| Ig Type | IgG1 |
| 克隆号 | 4M704 |
| 反应种属 | Human |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1/500-1/2000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human CD204 (AA: extra 275-451) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | MSR1 |
| 基因ID | |
| 蛋白名称 | Macrophage scavenger receptor types I and II |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |