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Anti-GRK2 Antibody (1Q719)

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货号 TMAB-06780

Anti-GRK2 Antibody (1Q719) 是一种 Rabbit 抗体，靶向 GRK2。Anti-GRK2 Antibody (1Q719) 可用于 WB,FCM,IHC-P,IHC-Fr,IF。

Anti-GRK2 Antibody (1Q719)

Anti-GRK2 Antibody (1Q719)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06780

Anti-GRK2 Antibody (1Q719) 是一种 Rabbit 抗体，靶向 GRK2。Anti-GRK2 Antibody (1Q719) 可用于 WB,FCM,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

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产品描述
Anti-GRK2 Antibody (1Q719) is a Rabbit antibody targeting GRK2. Anti-GRK2 Antibody (1Q719) can be used in WB,FCM,IHC-P,IHC-Fr,IF.
Ig Type
IgG/Kappa
克隆号
1Q719
反应种属
Human,Mouse,Rat
应用WBFCMIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; FCM: 1:50-100; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
组织特异性Expressed in peripheral blood leukocytes.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq].
抗原信息
基因名称
GRK2
基因ID
156
蛋白名称
beta-adrenergic receptor kinase 1
功能
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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