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Anti-Doublecortin/DCX Antibody (1Q732)
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产品编号 TMAY-02589
别名 XLIS, SCLH, LISX, doublecortin, DC, DBCN
Anti-Doublecortin/DCX Antibody (1Q732) 是一种 Mouse 抗体，靶向 Doublecortin/DCX。Anti-Doublecortin/DCX Antibody (1Q732) 可用于 ICC/IF。
Anti-Doublecortin/DCX Antibody (1Q732)
331 Anti-Doublecortin/DCX Antibody (1Q732)
还可以产品编号 TMAY-02589 别名 XLIS, SCLH, LISX, doublecortin, DC, DBCN
Anti-Doublecortin/DCX Antibody (1Q732) 是一种 Mouse 抗体，靶向 Doublecortin/DCX。Anti-Doublecortin/DCX Antibody (1Q732) 可用于 ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,684 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Doublecortin/DCX Antibody (1Q732) is a Mouse antibody targeting Doublecortin/DCX. Anti-Doublecortin/DCX Antibody (1Q732) can be used in ICC/IF. |
| 别名 | XLIS, SCLH, LISX, doublecortin, DC, DBCN |
| Ig Type | Mouse IgG2a |
| 克隆号 | 1Q732 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of Human DCX in HepG2 cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Human DCX monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm. |
| 应用 | ICC/IF |
| 推荐剂量 | ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, 0.02% Tween 80, pH7.0 |
| 研究背景 | DCX (doublecortin, N-GST chimera)contains 2 doublecortin domains and belongs to the doublecortin family. It is highly expressed in neuronal cells of fetal brain, but not expressed in other fetal tissues. In the adult, it is highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas. DCX is a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. It may act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. DCX may in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. It may be part with LIS-1 of a overlapping, but distinct, signaling pathways that promote neuronal migration. Defects in DCX are the cause of lissencephaly X-linked type 1 and subcortical band heterotopia X-linked. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human Doublecortin/DCX Protein (TMPY-02718) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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