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顶部生物活性储存和溶解信息计算器

Anti-NALP6 Polyclonal Antibody

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Anti-NALP6 Polyclonal Antibody
产品编号 TMAB-01200

Anti-NALP6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NALP6。Anti-NALP6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-NALP6 Polyclonal Antibody

Anti-NALP6 Polyclonal Antibody

Rating icon 还可以
Anti-NALP6 Polyclonal Antibody
产品编号 TMAB-01200

Anti-NALP6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NALP6。Anti-NALP6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-NALP6 Polyclonal Antibody is a Rabbit antibody targeting NALP6. Anti-NALP6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Mouse,Rat (predicted:Human)
验证活性
1. Tissue/cell: rat kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-NALP6 Polyclonal Antibody, Unconjugated (TMAB-01200) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
2. Tissue/cell: mouse intestine tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-NALP6 Polyclonal Antibody, Unconjugated (TMAB-01200) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
应用
IHC-P
IHC-Fr
IF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cytoplasm. Cell membrane. Nucleus membrane. Isoform 2: Cytoplasm. Cell membrane. Note=Predominantly expressed in the cell membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human NALP6
抗原种属
Human
基因ID
171389
Uniprot ID
P59044
研究领域
Caspases,Macrophage / Inflamm.,NFkB Pathway
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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