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Anti-NALP6 Polyclonal Antibody

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Anti-NALP6 Polyclonal Antibody
产品编号 TMAB-01200
别名 PYRIN containing APAF1 like protein 5, PYPAF5, PAN3, Nucleotide binding oligomerization domain, leucine rich repeat and pyrin domain containing 6, Nlrp6, NLR family, pyrin domain containing 6, NALP6, NACHT, LRR and PYD domains-containing protein 6, NACHT, LRR and PYD containing protein 6, NACHT, leucine rich repeat and PYD containing 6, CLR11.4

Anti-NALP6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NALP6。Anti-NALP6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-NALP6 Polyclonal Antibody

Anti-NALP6 Polyclonal Antibody

Rating icon 还可以
Anti-NALP6 Polyclonal Antibody
产品编号 TMAB-01200 别名 PYRIN containing APAF1 like protein 5, PYPAF5, PAN3, Nucleotide binding oligomerization domain, leucine rich repeat and pyrin domain containing 6, Nlrp6, NLR family, pyrin domain containing 6, NALP6, NACHT, LRR and PYD domains-containing protein 6, NACHT, LRR and PYD containing protein 6, NACHT, leucine rich repeat and PYD containing 6, CLR11.4

Anti-NALP6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NALP6。Anti-NALP6 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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生物活性
产品描述
Anti-NALP6 Polyclonal Antibody is a Rabbit antibody targeting NALP6. Anti-NALP6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
别名PYRIN containing APAF1 like protein 5, PYPAF5, PAN3, Nucleotide binding oligomerization domain, leucine rich repeat and pyrin domain containing 6, Nlrp6, NLR family, pyrin domain containing 6, NALP6, NACHT, LRR and PYD domains-containing protein 6, NACHT, LRR and PYD containing protein 6, NACHT, leucine rich repeat and PYD containing 6, CLR11.4
Ig Type
IgG
交叉反应
Mouse,Rat (predicted:Human)
验证活性
1. Tissue/cell: rat kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-NALP6 Polyclonal Antibody, Unconjugated (TMAB-01200) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
2. Tissue/cell: mouse intestine tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min;
Incubation: Anti-NALP6 Polyclonal Antibody, Unconjugated (TMAB-01200) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining.
应用
IHC-P
IHC-Fr
IF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cytoplasm. Cell membrane. Nucleus membrane. Isoform 2: Cytoplasm. Cell membrane. Note=Predominantly expressed in the cell membrane.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human NALP6
抗原种属
Human
基因ID
171389
Uniprot ID
P59044
研究领域
Caspases,Macrophage / Inflamm.,NFkB Pathway
化学信息
分子量Theoretical: 98 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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