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顶部生物活性储存和溶解信息计算器

Anti-CD47 Antibody (9X161)

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Anti-CD47 Antibody (9X161)
产品编号 TMAY-02309
别名 OA3, MER6, IAP, CD47 molecule

Anti-CD47 Antibody (9X161) 是一种 Mouse 抗体，靶向 CD47。Anti-CD47 Antibody (9X161) 可用于 FCM。

Anti-CD47 Antibody (9X161)
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Anti-CD47 Antibody (9X161)

Rating icon 还可以
Anti-CD47 Antibody (9X161)
产品编号 TMAY-02309 别名 OA3, MER6, IAP, CD47 molecule

Anti-CD47 Antibody (9X161) 是一种 Mouse 抗体，靶向 CD47。Anti-CD47 Antibody (9X161) 可用于 FCM。

规格价格库存数量
100 μL
¥ 1,694
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD47 Antibody (9X161) is a Mouse antibody targeting CD47. Anti-CD47 Antibody (9X161) can be used in FCM.
别名OA3, MER6, IAP, CD47 molecule
Ig Type
Mouse IgG1
克隆号
9X161
交叉反应
Human
验证活性
Flow cytometric analysis of Human CD47 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD47, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD47 (rh CD47; TMPY-04683; NP_942088.1; Met1-Pro139). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the brain. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. It may prevent premature elimination of red blood cells. It also may be involved in membrane permeability changes induced following virus infection. By acting as an adhesion receptor for THBS1 on platelets, CD47 plays a role in both cell adhesion and in the modulation of integrins. It also plays an important role in memory formation and synaptic plasticity in the hippocampus.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
其他可选修饰符
FITC/PE
可提供抗体种类
3
抗原信息
免疫原
Recombinant Protein: Human CD47 Protein (TMPY-04683)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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关键词

OA-3OA 3MER-6MER 6

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4个月前
5.0
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