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Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 15.19 kDa and the accession number is Q99988-1.

| 规格 | 价格 | 库存 | 数量 | 
|---|---|---|---|
| 5 μg | ¥ 793 | 6-8日内发货 | |
| 10 μg | ¥ 1,290 | 6-8日内发货 | |
| 20 μg | ¥ 2,190 | 5日内发货 | |
| 50 μg | ¥ 4,370 | 5日内发货 | |
| 100 μg | ¥ 7,410 | 5日内发货 | |
| 200 μg | ¥ 13,300 | 5日内发货 | |
| 500 μg | ¥ 29,600 | 5日内发货 | 
| 生物活性 | Immobilized Human GFRAL, hFc Tag at 1μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human GDF15, His Tag with the EC50 of 24ng/ml determined by ELISA. | 
| 产品描述 | Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 15.19 kDa and the accession number is Q99988-1. | 
| 种属 | Human | 
| 表达系统 | E. coli | 
| 标签 | N-His-Avi | 
| 蛋白编号 | Q99988-1 | 
| 别名 | RG-1,PTGF-β,PTGFBPTGF-β,PTGFBPTGF-beta,PTGF-beta,PTGFB,Placental TGF-β,Placental TGF-beta,PLAB,PDF,NAG-1,MIC-1,MIC1,GDF-15,GDF15 | 
| 蛋白构建 | Ala197-Ile308 | 
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE | 
| 分子量 | 15.19 kDa (predicted) same as Tris-Bis PAGE result. | 
| 内毒素 | < 1 EU/μg by the LAL method. | 
| 蛋白性状 | Lyophilized powder | 
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM HAc (pH 2.9). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. | 
| 复溶方法 | Reconstitute the lyophilized protein in 50mM HAc (pH 2.9). The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. | 
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. | 
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. | 
| 研究背景 | Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. |