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Anti-CD16/FCGR3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CD16/FCGR3。Anti-CD16/FCGR3 Polyclonal Antibody 可用于 WB。
Anti-CD16/FCGR3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CD16/FCGR3。Anti-CD16/FCGR3 Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,170 | 5日内发货 | |
100 μL | ¥ 1,975 | 5日内发货 | |
200 μL | ¥ 2,795 | 5日内发货 |
产品描述 | Anti-CD16/FCGR3 Polyclonal Antibody is a Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Sample: Raw264.7 (Mouse) Cell Lysate at 30 μg Primary: Anti-CD16 (TMAB-00337) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 27 kDa Observed band size: 50 kDa 2. Sample: Lane 1: Thymus (Rat) Lysate at 40 μg Lane 2: LympHnode (Mouse) Lysate at 40 μg Primary: Anti-CD16 (TMAB-00337) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 55 kDa Observed band size: 60 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cell membrane. Secreted. Exists also as a soluble receptor. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020] |
免疫原 | KLH conjugated synthetic peptide: human IGFR3/CD16 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | NK Cells,Human Lineage Negative,NK Cell Lineage,Monocytic Lineage,Neutrophil Lineage |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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