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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CD16/FCGR3 Polyclonal Antibody

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货号 TMAB-00337

别名 Fc receptor, IgG, low affinity III, CD16

Anti-CD16/FCGR3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD16/FCGR3。Anti-CD16/FCGR3 Polyclonal Antibody 可用于 WB。

Anti-CD16/FCGR3 Polyclonal Antibody

Anti-CD16/FCGR3 Polyclonal Antibody

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货号 TMAB-00337 别名 Fc receptor, IgG, low affinity III, CD16

Anti-CD16/FCGR3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD16/FCGR3。Anti-CD16/FCGR3 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD16/FCGR3 Polyclonal Antibody is a Rabbit antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Polyclonal Antibody can be used in WB.
别名Fc receptor, IgG, low affinity III, CD16
Ig Type
IgG
反应种属
Human,Mouse,Rat
验证活性
1. Sample:
Raw264.7 (Mouse) Cell Lysate at 30 μg
Primary: Anti-CD16 (TMAB-00337) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 27 kDa
Observed band size: 50 kDa
2. Sample:
Lane 1: Thymus (Rat) Lysate at 40 μg
Lane 2: LympHnode (Mouse) Lysate at 40 μg
Primary: Anti-CD16 (TMAB-00337) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kDa
Observed band size: 60 kDa
verifiedActivityverifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Secreted. Exists also as a soluble receptor.
组织特异性Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]
抗原信息
免疫原
KLH conjugated synthetic peptide: human IGFR3/CD16
抗原种属
Human
基因名称
FCGR3A
基因ID
2214
蛋白名称
Low affinity immunoglobulin gamma Fc region receptor III-A
Uniprot ID
P08637
研究领域
NK Cells,Human Lineage Negative,NK Cell Lineage,Monocytic Lineage,Neutrophil Lineage
功能
Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.
化学信息
分子量Theoretical: 27 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

CD-16CD 16
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