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Anti-ADAM15 Antibody (1K668)

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货号 TMAB-02282

Anti-ADAM15 Antibody (1K668) 是一种 Rabbit 抗体，靶向 ADAM15。Anti-ADAM15 Antibody (1K668) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-ADAM15 Antibody (1K668)

Anti-ADAM15 Antibody (1K668)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02282

Anti-ADAM15 Antibody (1K668) 是一种 Rabbit 抗体，靶向 ADAM15。Anti-ADAM15 Antibody (1K668) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADAM15 Antibody (1K668) is a Rabbit antibody targeting ADAM15. Anti-ADAM15 Antibody (1K668) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
1K668
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Endomembrane system; Single-pass type I membrane protein. Cell junction, adherens junction. Cell projection, cilium, flagellum (By similarity). Cytoplasmic vesicle, secretory vesicle, acrosome (By similarity). Note=The majority of the protein is localized in a perinuclear compartment which may correspond to the trans-Golgi network or the late endosome. The pro-protein is the major detectable form on the cell surface, whereas the majority of the protein in the cell is processed (By similarity).
组织特异性Expressed in colon and small intestine. Expressed in airway smooth muscle and glomerular mesangial cells (at protein level). Ubiquitously expressed. Overexpressed in atherosclerotic lesions. Constitutively expressed in cultured endothelium and smooth muscle. Expressed in chondrocytes. Expressed in airway smooth muscle and glomerular mesangial cells.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells.
抗原信息
免疫原
A synthesized peptide: human ADAM 15
抗原种属
Human
基因名称
ADAM15
基因ID
8751
蛋白名称
Disintegrin and metalloproteinase domain-containing protein 15
Uniprot ID
Q13444
功能
Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.
化学信息
分子量Theoretical: 93 kDa. Actual: 90, 100 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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