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顶部生物活性储存和溶解信息计算器

Anti-INPP5D Antibody (9H177)

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Anti-INPP5D Antibody (9H177)
产品编号 TMAC-03740
别名 SIP-145, SHIP-1, SHIP1, SHIP, SH2 domain-containing inositol phosphatase 1, SH2 domain-containing inositol 5'-phosphatase 1, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, p150Ship, Inositol polyphosphate-5-phosphatase of 145 kDa, hp51CN, EC 3.1.3.86

Anti-INPP5D Antibody (9H177) 是一种 Rabbit 抗体，靶向 INPP5D。Anti-INPP5D Antibody (9H177) 可用于 WB,IHC,IP,FCM。

Anti-INPP5D Antibody (9H177)

Anti-INPP5D Antibody (9H177)

Rating icon 还可以
Anti-INPP5D Antibody (9H177)
产品编号 TMAC-03740 别名 SIP-145, SHIP-1, SHIP1, SHIP, SH2 domain-containing inositol phosphatase 1, SH2 domain-containing inositol 5'-phosphatase 1, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, p150Ship, Inositol polyphosphate-5-phosphatase of 145 kDa, hp51CN, EC 3.1.3.86

Anti-INPP5D Antibody (9H177) 是一种 Rabbit 抗体，靶向 INPP5D。Anti-INPP5D Antibody (9H177) 可用于 WB,IHC,IP,FCM。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-INPP5D Antibody (9H177) is a Rabbit antibody targeting INPP5D. Anti-INPP5D Antibody (9H177) can be used in WB,IHC,IP,FCM.
别名SIP-145, SHIP-1, SHIP1, SHIP, SH2 domain-containing inositol phosphatase 1, SH2 domain-containing inositol 5'-phosphatase 1, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, p150Ship, Inositol polyphosphate-5-phosphatase of 145 kDa, hp51CN, EC 3.1.3.86
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of SHIP on different lysates using anti-SHIP antibody at 1/1,000 dilution. Positive control: Lane 1: Daudi, Lane 2: THP-1.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-SHIP antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-SHIP antibody. Counter stained with hematoxylin.
4. Flow cytometric analysis of Raji cells with SHIP antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
WB
IHC
IP
FCM
推荐剂量
WB: 1:1000; IHC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The major translational product of the v-Fms oncogene, originally isolated from the McDonough strain of feline sarcoma virus, has been identified as a glycoprotein with intrinsic tyrosine kinase activity. The v-Fms human cellular homolog, c-Fms, has been molecularly cloned and mapped to band q34 on chromosome 5, and identified as the receptor for hematopoietic ligand, CSF-1. Ligand-induced activation of the intrinsic CSF-1R protein tyrosine kinase triggers its interaction with cytoplasmic effector molecules. One such effector molecule, SHIP-1 p145 (SH2-containing-inositol phosphatase), associates with activated Fms. SHIP-1 contains two phosphotyrosine-binding domains (PTB), a unique amino terminal SH2 domain, a proline-rich region, and two highly conserved motifs found among inositol phosphate 5-phosphatases. SHIP-1 displays both phosphatidylinositol 3,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate polyphosphate 5-phosphatase activity. Evidence suggests that SHIP-1 may modulate Ras signaling in addition to inositol signaling pathways.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q92835
化学信息
分子量Theoretical: 133/109 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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