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Anti-NR3C1 Antibody (1M615)

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Anti-NR3C1 Antibody (1M615)
产品编号 TMAC-01671
别名 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), GRL, GR, GCRST, GCR, GCCR

Anti-NR3C1 Antibody (1M615) 是一种 Rabbit 抗体,靶向 NR3C1。Anti-NR3C1 Antibody (1M615) 可用于 WB,FCM。

Anti-NR3C1 Antibody (1M615)

Anti-NR3C1 Antibody (1M615)

Rating icon 还可以
Anti-NR3C1 Antibody (1M615)
产品编号 TMAC-01671 别名 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), GRL, GR, GCRST, GCR, GCCR

Anti-NR3C1 Antibody (1M615) 是一种 Rabbit 抗体,靶向 NR3C1。Anti-NR3C1 Antibody (1M615) 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,495
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-NR3C1 Antibody (1M615) is a Rabbit antibody targeting NR3C1. Anti-NR3C1 Antibody (1M615) can be used in WB,FCM.
别名nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor), GRL, GR, GCRST, GCR, GCCR
Ig Type
IgG
克隆号
1M615
交叉反应
Human,Mouse,Rat,zebrafish
验证活性
1. Western blot analysis of Glucocorticoid Receptor on different lysates using anti-Glucocorticoid Receptor antibody at 1/1,000 dilution. Positive control: Lane 1: zebrafish, Lane 2: A549, Lane 3: HepG2.
2. Western blot analysis of Glucocorticoid Receptor on hybrid fish (crucian-carp) heart tissue lysate using anti-Glucocorticoid Receptor antibody at 1/500 dilution.
3. Flow cytometric analysis of NIH/3T3 cells with Glucocorticoid Receptor antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:1000-5000; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that mediates the effects of glucocorticoids. The most abundant isoform is GR α. GR induces or represses the expression of genes in response to glucocorticoids, mediating such processes as apoptosis, cell growth and differentiation. A significant class of genes suppressed by GR is controlled by the transcription factor AP-1. GR has also been shown to be the limiting factor in the induction of gene expression by glucocorticoids. It has been revealed that GR forms a complex with HSP 90, rendering the non-ligand bound receptor transcriptionally inactive. More importantly, mutant GRs lacking the signaling domain remain constitutively active.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 86 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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