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Anti-CD204/MSR1 Antibody-FITC (4Z10) 是一种 FITC-conjugated Rabbit 抗体,靶向 CD204/MSR1。Anti-CD204/MSR1 Antibody-FITC (4Z10) 可用于 FCM。
Anti-CD204/MSR1 Antibody-FITC (4Z10) 是一种 FITC-conjugated Rabbit 抗体,靶向 CD204/MSR1。Anti-CD204/MSR1 Antibody-FITC (4Z10) 可用于 FCM。
产品描述 | Anti-CD204/MSR1 Antibody-FITC (4Z10) is a FITC-conjugated Rabbit antibody targeting CD204/MSR1. Anti-CD204/MSR1 Antibody-FITC (4Z10) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 4Z10 |
交叉反应 | Mouse |
验证活性 | Profile of anti-MSR1 (CD204) reactivity on Raw264.7 cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 prior to staining, washed, then stained with FITC Rabbit anti-MSR1 (CD204). |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse MSR1 / CD204 (rM MSR1 / CD204; TMPY-00528; AAH03814.1; Trp 83-Val 354) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
研究背景 | Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low-density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. |
偶联 | FITC |
其他可选修饰符 | Unconjugated/PE |
可提供抗体种类 | 3 |
免疫原 | Recombinant Mouse MSR1 / CD204 protein (TMPY-00528) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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