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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Caveolin-1 Antibody (1D910)

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货号 TMAB-03703

Anti-Caveolin-1 Antibody (1D910) 是一种 Rabbit 抗体，靶向 Caveolin-1。Anti-Caveolin-1 Antibody (1D910) 可用于 IHC-P,IHC-Fr,IF。

Anti-Caveolin-1 Antibody (1D910)

Anti-Caveolin-1 Antibody (1D910)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03703

Anti-Caveolin-1 Antibody (1D910) 是一种 Rabbit 抗体，靶向 Caveolin-1。Anti-Caveolin-1 Antibody (1D910) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Caveolin-1 Antibody (1D910) is a Rabbit antibody targeting Caveolin-1. Anti-Caveolin-1 Antibody (1D910) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
1D910
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae.
组织特异性Expressed in muscle and lung, less so in liver, brain and kidney.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液PBS, Glycerol, BSA.
浓度1mg/ml
研究背景The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Caveolin-1
抗原种属
Human
基因名称
CAV1
基因ID
857
蛋白名称
Caveolin-1
Uniprot ID
Q03135
功能
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
化学信息
分子量Theoretical: 20 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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