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Anti-NKX3A Antibody (1T251) 是一种 Mouse 抗体,靶向 NKX3A。Anti-NKX3A Antibody (1T251) 可用于 WB,IHC,FCM。
Anti-NKX3A Antibody (1T251) 是一种 Mouse 抗体,靶向 NKX3A。Anti-NKX3A Antibody (1T251) 可用于 WB,IHC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,995 | 5日内发货 | |
100 μL | ¥ 2,995 | 5日内发货 |
产品描述 | Anti-NKX3A Antibody (1T251) is a Mouse antibody targeting NKX3A. Anti-NKX3A Antibody (1T251) can be used in WB,IHC,FCM. |
别名 | NKX31_HUMAN, Nkx3-1, Nkx3.1, mouse, homolog of, NKX3.1, NKX3 1, NKX3, NKX 3A, Nkx 3.1, NKX 3, NK3 transcription factor related locus 1, NK3 transcription factor homolog A, NK3 homeobox 1, NK homeobox, family 3, member A, NK homeobox family 3 A, NK homeobox (Drosophila) family 3 A, Homeobox protein Nkx-3.1, Homeobox protein Nkx3.1, Homeobox protein Nkx 3.1, Homeobox protein NK-3 homolog A, BAPX2, BAPX 2 |
交叉反应 | Human |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; FCM: 1:100-200 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
研究背景 | The homeobox gene Nkx-3.1 is the human homolog of Drosophila bagpipe, which, in conjunction with tinman, determines cell fate in the dorsal mesoderm. In mammalian species, Nkx-3.1 is predominantly expressed in prostate, and it regulates prostate development in response to sonic hedgehog (Shh) signaling by exerting growth-suppressive and differentiating effects on prostatic epithelium. Nkx-3.1 is also expressed at lower levels in other tissues, including the heart and gut, in a Shh independent manner, where it plays a role in regulating proliferation of glandular epithelium and in the formation of ducts in prostate and minor salivary glands. Nkx-3.1 preferentially binds the TAAGTA sequence, which has not been reported for any other NK class homeoprotein. The human Nkx-3.1 gene is located on chromosome 8q21, which frequently undergoes a loss of heterozygosity, and although Nkx-3.1 is not a tumor suppressor gene, it may be a useful marker for benign and malignant prostate epithelium. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 26 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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