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Anti-KIRREL3 Polyclonal Antibody

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货号 TMAB-08079

Anti-KIRREL3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KIRREL3。Anti-KIRREL3 Polyclonal Antibody 可用于 FCM。

Anti-KIRREL3 Polyclonal Antibody

Anti-KIRREL3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08079

Anti-KIRREL3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KIRREL3。Anti-KIRREL3 Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-KIRREL3 Polyclonal Antibody is a Rabbit antibody targeting KIRREL3. Anti-KIRREL3 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein
组织特异性Expressed in fetal and adult brain. Also expressed in kidney, specifically in podocytes of kidney glomeruli.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景NEPH2 is a 778 amino acid single-pass type I membrane protein that belongs to the nephrin-like protein family and immunoglobulin superfamily. Expressed in both fetal and adult brain, as well as podocytes of kidney glomeruli, NEPH2 contains five Ig-like C2-type (immunoglobulin-like) domains and is thought to plaly a role in the hematopoetic supportive capacity of stroma cells. NEPH2 undergoes alternative splicing to produce two isoforms and contains a C-terminal cytoplasmic domain which it uses to interact with Podocin, a podocyte protein involved in ultrafiltration. Defects in the gene encoding NEPH2 are associated with mental retardation autosomal dominant type 4 (MRD4).
抗原信息
免疫原
KLH conjugated synthetic peptide: human KIRREL3
抗原种属
Human
基因名称
KIRREL3
基因ID
蛋白名称
Kin of IRRE-like protein 3
Uniprot ID
功能
NEPH2 is a member of the nephrin like protein family, which includes NEPH1 (KIRREL; MIM 607428) and NEPH3 (KIRREL2; MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size and charge selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).
化学信息
分子量Theoretical: 83 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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