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Anti-TOMM20 Polyclonal Antibody

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Anti-TOMM20 Polyclonal Antibody
产品编号 TMAB-01878

Anti-TOMM20 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TOMM20。Anti-TOMM20 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。

Anti-TOMM20 Polyclonal Antibody

Anti-TOMM20 Polyclonal Antibody

Rating icon 还可以
Anti-TOMM20 Polyclonal Antibody
产品编号 TMAB-01878

Anti-TOMM20 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 TOMM20。Anti-TOMM20 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍

生物活性
产品描述
Anti-TOMM20 Polyclonal Antibody is a Rabbit antibody targeting TOMM20. Anti-TOMM20 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
Sample:
Lane 1: Mouse Kidney Lysates
Lane 2: Mouse Brain Lysates
Lane 3: Mouse Heart Lysates
Lane 4: Mouse NIH/3T3 Lysates
Lane 5: Rat Kidney Lysates
Lane 6: Rat Brain Lysates
Lane 7: Rat Heart Lysates
Lane 8: Human Hela cell Lysates
Lane 9: Human THP-1 cell Lysates
Lane 10: Human HL-60 cell Lysates
Lane 11: Human 293T cell Lysates
Primary: Anti-TOMM20 (TMAB-01878) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 16 kDa
Observed band size: 16 kDa
应用
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Mitochondrion outer membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景The mitochondrial preprotein translocases of the outer membrane (Tom) is a multisubunit protein complex that facilitates the import of nucleus-encoded precursor proteins across the mitochondrial outer membrane (1). The Tom machinery consists of import receptors for the initial binding of cytosolically synthesized preproteins and a general import pore (GIP) for the membrane translocation of various preproteins into the mitochondria (2). The import receptors include Tom20 and Tom22, which form a heteromeric receptor complex that initiates the insertion of newly synthesized proteins into the outer membrane and then directs the precursor protein into the GIP (3,4). In yeast, Tom22 is the essential component of the import receptor complex as it functions as both a receptor for the preproteins and serves as a docking point for both Tom20 and the GIP (5,6). Tom22 directly associates with Tom40, the major component of the GIP, and thereby forms a stable interaction between the two core complexes to facilitate the fluid movement of preproteins into the mitochondria (6,7). The insertion of Tom40 into the Tom machinery requires the initial binding of Tom40 to Tom20 and leads to the efficient incorporation of Tom40 precursors into preexisting Tom complexes (2,8)
抗原信息
免疫原
KLH conjugated synthetic peptide: human TOM20
抗原种属
Human
基因ID
Uniprot ID
研究领域
Mitochondrial Biogenesis,Mitochondrial markers,Mitochondrial,Regulation
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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