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Anti-JAK1 Antibody (7B560)

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货号 TMAB-07857

Anti-JAK1 Antibody (7B560) 是一种 Rabbit 抗体，靶向 JAK1。Anti-JAK1 Antibody (7B560) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-JAK1 Antibody (7B560)

Anti-JAK1 Antibody (7B560)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07857

Anti-JAK1 Antibody (7B560) 是一种 Rabbit 抗体，靶向 JAK1。Anti-JAK1 Antibody (7B560) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-JAK1 Antibody (7B560) is a Rabbit antibody targeting JAK1. Anti-JAK1 Antibody (7B560) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
克隆号
7B560
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Endomembrane system; Peripheral membrane protein. Note=Wholly intracellular, possibly membrane associated.
组织特异性Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Janus kinase 1 (JAK1) is a member of a new class of non-receptor protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. The second phosphotransferase domain bears all the hallmarks of a protein kinase, although its structure differs significantly from that of the PTK and threonine/serine kinase family members. JAK1 is a large, widely expressed membrane-associated phosphoprotein. It is involved in the interferon-alpha/beta and -gamma signal transduction pathways. The reciprocal interdependence between JAK1 and TYK2 activities in the interferon-alpha pathway, and between JAK1 and JAK2 in the interferon-gamma pathway, may reflect a requirement for these kinases in the correct assembly of interferon recpeptor complexes. These kinases couple cytokine ligand binding to tyrosine phosphorylation of various known signaling proteins and a unique family of transcription factors termed the signal transducers and activators of transcription, or STATs.
抗原信息
免疫原
A synthesized peptide: human JAK1
抗原种属
Human
基因名称
JAK1
基因ID
3716
蛋白名称
Tyrosine-protein kinase JAK1
Uniprot ID
P23458
功能
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
化学信息
分子量Theoretical: 133 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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