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LY6G6D Protein, Human, Recombinant (hFc)

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货号 TMPK-00752

别名 Protein Ly6-D, NG25, MEGT1, Ly6-D, G6D, C6orf23

LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy. LY6G6D Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 35.87 kDa and the accession number is O95868.

LY6G6D Protein, Human, Recombinant (hFc)
其他形式的 “LY6G6D Protein, Human, Recombinant (hFc)”:
LY6G6D Protein, Human, Recombinant (His)
LY6G6D Protein, Human, Recombinant (His & Strep-II)
LY6G6D Protein, Cynomolgus, Recombinant (His)
LY6G6D Protein, Cynomolgus, Recombinant (Yeast, His)
NG 25 (hydrochloride hydrate)
NG25
NG25 trihydrochloride

LY6G6D Protein, Human, Recombinant (hFc)

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Rating icon 还可以
SPR兼容缓冲液
货号 TMPK-00752 别名 Protein Ly6-D, NG25, MEGT1, Ly6-D, G6D, C6orf23

LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy. LY6G6D Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 35.87 kDa and the accession number is O95868.

规格价格库存数量
5 μg
¥ 343
6-8日内发货
10 μg
¥ 549
6-8日内发货
20 μg
¥ 898
5日内发货
50 μg
¥ 1,760
5日内发货
100 μg
¥ 2,960
5日内发货
200 μg
¥ 5,350
5日内发货
500 μg
¥ 11,800
5日内发货
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产品介绍

生物活性
产品描述
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy. LY6G6D Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 35.87 kDa and the accession number is O95868.
生物活性
Immobilized Human LY6G6D, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-LY6G6D Antibody, hFc Tag with the EC50 of 14.6ng/ml determined by ELISA.
研究背景
LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.
种属
Human
表达系统
HEK293 Cells
标签C-hFc
蛋白编号O95868
蛋白构建Asn20-Ser104
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名Protein Ly6-D, NG25, MEGT1, Ly6-D, G6D, C6orf23
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量35.87 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

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关键词

NG-25NG 25MEGT-1MEGT 1
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