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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IGFBP-5 Polyclonal Antibody

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货号 TMAB-00924

别名 insulin-like growth factor binding protein 5, IBP5

Anti-IGFBP-5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IGFBP-5。Anti-IGFBP-5 Polyclonal Antibody 可用于 WB。

Anti-IGFBP-5 Polyclonal Antibody

Anti-IGFBP-5 Polyclonal Antibody

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货号 TMAB-00924 别名 insulin-like growth factor binding protein 5, IBP5

Anti-IGFBP-5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IGFBP-5。Anti-IGFBP-5 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-IGFBP-5 Polyclonal Antibody is a Rabbit antibody targeting IGFBP-5. Anti-IGFBP-5 Polyclonal Antibody can be used in WB.
别名insulin-like growth factor binding protein 5, IBP5
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Sheep)
验证活性
Sample:
Kidney (Mouse) Lysate at 40 μg
Primary: Anti-IGFBP5 (TMAB-00924) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 30 kDa
Observed band size: 30 kDa
verifiedActivity
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Osteosarcoma, and at lower levels in liver, kidney and brain.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景IGFBP5 is one of a family of proteins that bind to insulin-like growth factors (IGFs). IGFBP5 is a multifunctional protein which acts not only as a traditional binding protein but also functions as a growth factor independent of IGFs to stimulate bone formation. Currently there are seven named IGF-BPs that form high affinity complexes with both IGFI and IGFII. IGFBP5 is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGFI on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development. Function : IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
抗原信息
免疫原
KLH conjugated synthetic peptide: human IGFBP5
抗原种属
Human
基因名称
IGFBP5
基因ID
3488
蛋白名称
Insulin-like growth factor-binding protein 5
Uniprot ID
P24593
研究领域
Insulin / Insulin-like,Lipid Signaling
功能
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
化学信息
分子量Theoretical: 30 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

IBP-5IBP 5
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