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别名 VMA6, VMA 6, V-ATPase D2, Vacuolar proton pump subunit d 2, Vacuolar ATP synthase subunit d 2, VA0D2, V ATPase subunit d 2, FLJ38708, ATPase H+transporting lysosomal 38kDa V0 subunit D2, ATPase H+transporting lysosomal 38kDa V0 subunit D isoform 2, ATPase H+transporting lysosomal 38kDa V0 subunit D, ATP6D2
Anti-ATP6V0D2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ATP6V0D2。Anti-ATP6V0D2 Polyclonal Antibody 可用于 WB。
Anti-ATP6V0D2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ATP6V0D2。Anti-ATP6V0D2 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-ATP6V0D2 Polyclonal Antibody is a Rabbit antibody targeting ATP6V0D2. Anti-ATP6V0D2 Polyclonal Antibody can be used in WB. |
| 别名 | VMA6, VMA 6, V-ATPase D2, Vacuolar proton pump subunit d 2, Vacuolar ATP synthase subunit d 2, VA0D2, V ATPase subunit d 2, FLJ38708, ATPase H+transporting lysosomal 38kDa V0 subunit D2, ATPase H+transporting lysosomal 38kDa V0 subunit D isoform 2, ATPase H+transporting lysosomal 38kDa V0 subunit D, ATP6D2 |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Dog,Pig,Sheep) |
| 验证活性 | Sample: Lane 1: Human HeLa cell lysates Lane 2: Human A549 cell lysates Primary: Anti-ATP6V0D2 (TMAB-00169) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 40 kDa ![]() |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Apical plasma membrane. |
| 组织特异性 | Kidney, osteoclast and lung. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and a integral V0 domain, which is responsible for proton translocation, compose V-ATPase. Nine subunits (A–H) make up the V1 domain and five subunits (a, d, c, c' and c") make up the V0 domain. Like F-ATPase, V-ATPase most likely operates through a rotary mechanism. V-ATPase D2 is a 350 amino acid protein that is expressed in kidney, lung and osteoclast. V-ATPase D2 has been implicated as a regulator of urine acidification, osteoclast fusion and bone formation. Furthermore, V-ATPase D2 has been identified as a dendritic cell marker. |
| 免疫原 | KLH conjugated synthetic peptide: human ATP6V0D2/V-ATPase D2 |
| 抗原种属 | Human |
| 基因名称 | ATP6V0D2 |
| 基因ID | |
| 蛋白名称 | V-type proton ATPase subunit d 2 |
| Uniprot ID | |
| 研究领域 | ATPases |
| 功能 | Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity). |
| 分子量 | Theoretical: 40 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |