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FGF-7/KGF Protein, Human, Recombinant (His)

产品编号 TMPY-00403

FGF-7/KGF Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 21 kDa and the accession number is P21781.

FGF-7/KGF Protein, Human, Recombinant (His)

产品编号 TMPY-00403

FGF-7/KGF Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 21 kDa and the accession number is P21781.

规格	价格	库存
5 μg	¥ 396	6-8日内发货
10 μg	¥ 638	6-8日内发货
20 μg	¥ 1,050	In stock
50 μg	¥ 1,870	5日内发货
100 μg	¥ 2,930	5日内发货
200 μg	¥ 5,220	5日内发货

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产品信息

生物活性	Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human FGFR2b. The ED50 for this effect is typically 3-20 ng/mL.
产品描述	FGF-7/KGF Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 21 kDa and the accession number is P21781.
种属	Human
表达系统	E. coli
标签	N-His
蛋白编号	P21781
别名	成纤维细胞生长因子,KGF,HBGF-7,fibroblast growth factor 7
蛋白构建	A DNA sequence encoding the human KGF (P21781) (Cys32-Thr194) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His
蛋白纯度	≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
分子量	21 kDa (predicted); 23 kDa (reducing conditions)
内毒素	< 0.01 EU/μg of the protein.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 250 mM NaCl, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Fibroblast growth factor 7 (FGF7) is a member of the fibroblast growth factor (FGF) family of proteins. FGF7 plays an important role in regulating the proliferation, migration, and differentiation of cells. FGF7 is of stromal origin and produces a paracrine effect on epithelial cells. FGF7 is a mesenchyme-specific heparin-binding growth factor that binds FGF receptor 2 (FGFR2) to regulate numerous cellular and physiological processes. FGF7/FGFR2 promotes invasion and migration in human gastric cancer. FGF7 is specifically utilized as a paracrine factor during the process of differentiation of the epidermal layers in the regenerating scales and in particular for beta-cells differentiation. FGF7 over expression is associated with advanced clinical features in patients with upper tract and bladder urothelial carcinoma, justifying its potential prognostic value for urothelial carcinoma.