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Latent TGF beta 1 Protein, Mouse, Recombinant (His) V2

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产品编号 TMPY-00500U

Latent TGF beta 1 Protein, Mouse, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P04202.

Latent TGF beta 1 Protein, Mouse, Recombinant (His) V2

一键复制产品信息

产品编号 TMPY-00500U

Latent TGF beta 1 Protein, Mouse, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P04202.

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生物活性	Immobilized Mouse Latent TGF beta 1, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human ITGAV&ITGB6, hFc Tag with the EC50 of 0.59 μg/ml determined by ELISA.
产品描述	Latent TGF beta 1 Protein, Mouse, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P04202.
种属	Mouse
表达系统	HEK293 Cells
蛋白编号	P04202
别名	转化生长因子,transforming growth factor, β1,transforming growth factor, beta 1,TGF-β1,TGFβ1,TGF-beta1,TGFbeta1,Tgfb-1,Tgfb,TGF β1
蛋白构建	Leu30-Ser390
蛋白纯度	> 95% as determined by Tris-Bis PAGE
分子量	29.5/12.9 kDa (Predicted); 40-50/14-15 kDa (Due to glycosylation)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Latent TGF beta 1 cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin‑like convertase processes the proprotein to generate an N‑terminal 249 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 1. Disulfide‑linked homodimers of LAP and TGF‑ beta 1 remain non‑covalently associated after secretion, forming the small latent TGF‑ beta 1 complex.