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Anti-Claudin-11 Polyclonal Antibody

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货号 TMAB-00440

别名 OTM, OSP, claudin 11

Anti-Claudin-11 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Claudin-11。Anti-Claudin-11 Polyclonal Antibody 可用于 ELISA,IF,IHC-Fr,IHC-P。

Anti-Claudin-11 Polyclonal Antibody

Anti-Claudin-11 Polyclonal Antibody

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货号 TMAB-00440 别名 OTM, OSP, claudin 11

Anti-Claudin-11 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Claudin-11。Anti-Claudin-11 Polyclonal Antibody 可用于 ELISA,IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-Claudin-11 Polyclonal Antibody is a Rabbit antibody targeting Claudin-11. Anti-Claudin-11 Polyclonal Antibody can be used in ELISA,IF,IHC-Fr,IHC-P.
别名OTM, OSP, claudin 11
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig)
应用ELISAIFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景Oligodendrocyte specific protein (OSP)is the third most abundant component of central nervous system myelin. The claudin superfamily consists of many structurally related proteins. These proteins, which include claudin 1 through 18, are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. There is growing evidence that OSP/Claudin 11 determines the permeability between layers of myelin sheaths via focal adhesion. Its expression is highly regulated during development, suggesting that it may play an important role in the growth and differentiation of oligodendrocytes and other cells outside the CNS. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Claudin-11
抗原种属
Human
基因名称
CLDN11
基因ID
蛋白名称
Claudin-11
Uniprot ID
研究领域
Autoimmune,Oligodendrocyte marker,Neurodegenerative disease
化学信息
分子量Theoretical: 22 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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