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Anti-Claudin-11 Polyclonal Antibody
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产品编号 TMAB-00440
Anti-Claudin-11 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Claudin-11。Anti-Claudin-11 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,ELISA。
Anti-Claudin-11 Polyclonal Antibody
Anti-Claudin-11 Polyclonal Antibody
还可以产品编号 TMAB-00440
Anti-Claudin-11 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Claudin-11。Anti-Claudin-11 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-Claudin-11 Polyclonal Antibody is a Rabbit antibody targeting Claudin-11. Anti-Claudin-11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,ELISA. |
| Ig Type | IgG |
| 交叉反应 | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig) |
| 应用 | |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | Oligodendrocyte specific protein (OSP)is the third most abundant component of central nervous system myelin. The claudin superfamily consists of many structurally related proteins. These proteins, which include claudin 1 through 18, are located in both epithelial and endothelial cells in all tight junction bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. There is growing evidence that OSP/Claudin 11 determines the permeability between layers of myelin sheaths via focal adhesion. Its expression is highly regulated during development, suggesting that it may play an important role in the growth and differentiation of oligodendrocytes and other cells outside the CNS. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease. |
| 免疫原 | KLH conjugated synthetic peptide: human Claudin-11 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Autoimmune,Oligodendrocyte marker,Neurodegenerative disease |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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