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Anti-PAK2 Antibody (4F579)

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货号 TMAB-09939

Anti-PAK2 Antibody (4F579) 是一种 Rabbit 抗体，靶向 PAK2。Anti-PAK2 Antibody (4F579) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-PAK2 Antibody (4F579)

Anti-PAK2 Antibody (4F579)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09939

Anti-PAK2 Antibody (4F579) 是一种 Rabbit 抗体，靶向 PAK2。Anti-PAK2 Antibody (4F579) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-PAK2 Antibody (4F579) is a Rabbit antibody targeting PAK2. Anti-PAK2 Antibody (4F579) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
克隆号
4F579
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm and Nucleus. Cytoplasm > perinuclear region. Membrane. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane.
组织特异性Ubiquitously expressed. Higher levels seen in skeletal muscle, ovary, thymus and spleen.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation.Acts as a downstream effector of the small GTPases CDC42 and RAC1.Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues.
抗原信息
免疫原
A synthesized peptide: human PAK2
抗原种属
Human
基因名称
PAK2
基因ID
5062
蛋白名称
Serine/threonine-protein kinase PAK 2
Uniprot ID
Q13177
功能
The activated kinase acts on a variety of targets. Phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. Full length PAK 2 stimulates cell survival and cell growth. The process is, at least in part, mediated by phosphorylation and inhibition of pro-apoptotic BAD. Caspase-activated PAK-2p34 is involved in cell death response, probably involving the JNK signaling pathway. Cleaved PAK-2p34 seems to have a higher activity than the CDC42-activated form.
化学信息
分子量Theoretical: 58 kDa. Actual: 61 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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