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Anti-FHL2 Antibody (9R411) 是一种 Rabbit 抗体,靶向 FHL2。Anti-FHL2 Antibody (9R411) 可用于 WB,IHC,IP。
Anti-FHL2 Antibody (9R411) 是一种 Rabbit 抗体,靶向 FHL2。Anti-FHL2 Antibody (9R411) 可用于 WB,IHC,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-FHL2 Antibody (9R411) is a Rabbit antibody targeting FHL2. Anti-FHL2 Antibody (9R411) can be used in WB,IHC,IP. |
别名 | SLIM-3, SLIM3, SLIM 3, Skeletal muscle LIM-protein 3, Skeletal muscle LIM protein 3, LIM domain protein DRAL, KIAA0990, Four and a half LIM domains protein 2, Four and a half LIM domains 2, Four and a half LIM domain protein 2, FHL2_HUMAN, FHL2 protein, FHL-2, Fhl2, FHL 2, DRAL, Downregulated in rhabdomyosarcoma LIM protein, Down regulated in rhabdomyosarcoma LIM protein, Aging associated gene 11, AAG11, AAG 11 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of FHL2 on different tissue lysates using anti-FHL2 antibody at 1/1,000 dilution. Positive control: Lane 1: Rat heart, Lane 2: Mouse heart. 2. Immunohistochemical analysis of paraffin-embedded rat heart tissue using anti-FHL2 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human fetal heart tissue using anti-FHL2 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-FHL2 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC: 1:50-200; IP: 1:10-50 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The four-and-a-half-LIM domain (FHL) proteins include FHL-1 (SLIM1), FHL-2 (SLIM3), FHL-3 (SLIM2) and FHL-4. The signature "half-domain", a single zinc finger domain located in the N-terminal region, differentiates FHLs from other LIM-only proteins, which have numbers of zinc fingers. Specific combinations of FHL proteins elicit selective activation of both CREB and CREM. Skeletal and cardiac muscle express FHL-1 in high levels as compared to the low level of expression in smooth muscle of the colon, small intestine and prostate. FHL-1 localizes to the cytosol of myoblasts, myotubes, and differentiated myocytes. FHL-2 is also located in cardiac and skeletal muscle, as well as in placenta and ovary tissues. FHL-3 is found in skeletal muscle, but absent in cardiac muscle. FHL-4 is expressed exclusively by the seminiferous epithelium of the testis, which suggests that FHL-4 is involved in spermatogenesis. The genetic loci for FHLs vary considerably despite similiar amino acid sequences among the FHL group. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: within C-terminal human FHL2 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 32 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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