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CAPN2 Protein, Human, Recombinant (His)

CAPN2 Protein, Human, Recombinant (His)

产品编号 TMPH-01031
别名: Calpain-2 catalytic subunit, Millimolar-calpain, Calpain-2 large subunit, Calpain M-type, M-calpain, CANP 2, CANPL2, CAPN2, Calpain large polypeptide L2, Calcium-activated neutral proteinase 2

Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. CAPN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 82.1 kDa and the accession number is P17655.

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CAPN2 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
20 μg ¥ 1,320 现货
100 μg ¥ 2,470 20日内发货
1 mg ¥ 10,700 20日内发货
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产品目录号及名称: CAPN2 Protein, Human, Recombinant (His) (TMPH-01031)
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产品描述 Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. CAPN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 82.1 kDa and the accession number is P17655.
种属 Human
表达系统 E. coli
标签 N-6xHis
蛋白编号 P17655
别名 Calpain-2 catalytic subunit, Millimolar-calpain, Calpain-2 large subunit, Calpain M-type, M-calpain, CANP 2, CANPL2, CAPN2, Calpain large polypeptide L2, Calcium-activated neutral proteinase 2
氨基酸序列 SHDRAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGFKELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEILARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSALLEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGCSIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDNCPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTKMDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL
蛋白构建 20-700 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 82.1 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs.

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Keywords

CAPN2 Protein, Human, Recombinant (His) Calpain-2 catalytic subunit Millimolar-calpain Calpain-2 large subunit Calpain M-type M-calpain CANP 2 CANPL2 CAPN2 Calpain large polypeptide L2 Calcium-activated neutral proteinase 2 recombinant recombinant-proteins proteins protein

 

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