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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-JMJD1B Polyclonal Antibody

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货号 TMAB-07870

Anti-JMJD1B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 JMJD1B。Anti-JMJD1B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-JMJD1B Polyclonal Antibody

Anti-JMJD1B Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07870

Anti-JMJD1B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 JMJD1B。Anti-JMJD1B Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-JMJD1B Polyclonal Antibody is a Rabbit antibody targeting JMJD1B. Anti-JMJD1B Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景JMJD1B (jumonji domain containing 1B), also known as KDM3B, 5qNCA (5q Nuclear Co-Activator) or C5orf7, is a member of the JHDM2 histone demethylase family of proteins. Expressed in a wide variety of tissues, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif. JMJD1B functions as a histone demethylase and, using iron as a cofactor, demethylates lysine-9 of Histone H3. This suggests that JMJD1B plays a central role in the histone code. The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias. This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia. Eptopic expression of JMJD1B exhibits growth suppressive activities, further supporting a role for JMJD1B in tumor suppression.
抗原信息
免疫原
KLH conjugated synthetic peptide: human JMJD1B
抗原种属
Human
基因名称
KDM3B
基因ID
51780
蛋白名称
Lysine-specific demethylase 3B
Uniprot ID
Q7LBC6
功能
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
化学信息
分子量Theoretical: 190 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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