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Anti-Latexin Antibody (1T982) 是一种 Rabbit 抗体,靶向 Latexin。Anti-Latexin Antibody (1T982) 可用于 ELISA。
Anti-Latexin Antibody (1T982) 是一种 Rabbit 抗体,靶向 Latexin。Anti-Latexin Antibody (1T982) 可用于 ELISA。
产品描述 | Anti-Latexin Antibody (1T982) is a Rabbit antibody targeting Latexin. Anti-Latexin Antibody (1T982) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 1T982 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Latexin / LXN (rM Latexin / LXN; TMPY-01771; NP_058033.2; Glu 2-Glu 222). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly expressed in the heart, prostate, ovary, kidney, pancreas, and colon. Latexin / LXN is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional specification of the neocortex in development in rats. The 222 amino acid latexin in the human shows different expression distribution with high levels in heart, prostate, ovary, kidney, pancreas, and colon, but only moderate or low levels in other tissues including the brain. Latexin is also expressed at high levels and is inducible in macrophages in concert with other protease inhibitors and potential protease targets, and thus is suggested to play a role in inflammation and innate immunity pathways. Despite the non-detectable sequence similarity with plant and parasite inhibitors, Latexin is related to a human putative tumor suppressor protein, TIG1. Also, Latexin is implicated in Alzheimer's disease. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse Latexin / LXN protein (TMPY-01771) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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