LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.9 kDa and the accession number is D9IDM8.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
50 μg | ¥ 2,260 | 现货 | ||
100 μg | ¥ 4,010 | 5日内发货 | ||
200 μg | ¥ 7,090 | 5日内发货 | ||
500 μg | ¥ 15,000 | 5日内发货 |
生物活性 | Testing in progress |
产品描述 | LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.9 kDa and the accession number is D9IDM8. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-hFc |
蛋白编号 | D9IDM8 |
别名 | ILT-2, LIR-1, CD85j, LIR1, MIR7, leukocyte immunoglobulin like receptor B1, ILT2, XXbac-BCX85G21.4, MIR-7 |
蛋白构建 | The Human LILRB1 (ADJ55949.1) (Met1-His458) was expressed with the Fc region of Human IgG1 at the C-terminus. |
蛋白纯度 |
≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
|
分子量 | 73.9 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | LILRB1 (Leukocyte Immunoglobulin Like Receptor B1) is a Protein Coding gene. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). LILRB1 is encoded within the leukocyte receptor complex on 19q13.4, previously implicated to be a susceptibility region to systemic lupus erythematosus (SLE). LILRB1 binds to a wide range of Major Histocompatibility Complex Class I molecules (MHCIs) and transduces negative signals that can, for example, prevent the killing of MHCI-expressing cells. LILRB1 transcription is correlated with surface protein expression on NK cells. Diseases associated with LILRB1 include Alzheimer's Disease 12 and Severe Pre-Eclampsia. |
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LILRB1/CD85j/ILT2 Protein, Human, Recombinant (hFc) ILT-2 LIR-1 CD85j LIR1 MIR7 LIR 1 leukocyte immunoglobulin like receptor B1 ILT2 MIR 7 XXbac-BCX85G21.4 MIR-7 ILT 2 recombinant recombinant-proteins proteins protein