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Anti-Phospho-MITF (Ser180, 73) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MITF (Ser180, 73)。Anti-Phospho-MITF (Ser180, 73) Polyclonal Antibody 可用于 WB。
Anti-Phospho-MITF (Ser180, 73) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-MITF (Ser180, 73)。Anti-Phospho-MITF (Ser180, 73) Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,230 | 5日内发货 |
产品描述 | Anti-Phospho-MITF (Ser180, 73) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MITF (Ser180, 73). Anti-Phospho-MITF (Ser180, 73) Polyclonal Antibody can be used in WB. |
别名 | p-MITF (Ser180, 73), p-MITF (S180, 73), MITF (p-Ser180, 73), MITF (p-S180, 73) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of extracts from Mouse brain tissue using MITF (Phospho-Ser180/73) Antibody TMAC-02588. The lane on the right is treated with the antigen-specific peptide. |
应用 | |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | Transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of Serine 180(P-N-S(p)-P-M)/Serine 73(Q-E-R(p)-R-E) derived from Human MITF |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 52 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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